Our Walterboro SC Hotel Guests “Stay Smart” Conveniently situated in the heart of the Lowcountry, and newly renovated, this Walterboro, South Carolina hotel is the perfect place to stopover. You’ll love exploring downtown’s shopping, dining and historic sites and the blackwater rivers and cypress forests surrounding the Holiday Inn Express® Hotel & Suites Walterboro I – 95. Our hotel’s corporate guests appreciate our location near some of the area’s notable businesses, including the Colleton Medical Center, VA Hospital, Canady’s Steam Plant, Dayco Products and Carolina Textile Recycling. Additionally, the free high-speed internet access in every room and a 24-hour business...