Enjoy our Huntsville, TX Hotel’s First-Rate Accommodations One of the oldest cities in the Lone Star State, Huntsville is home to a number of businesses and attractions, and it’s the type of place that proudly exemplifies the hospitality of “small-town Texas.” If you’re visiting, “Stay Smart” with us at the Holiday Inn Express® Hotel & Suites Huntsville, which is conveniently located off I-45 and just 70 miles from Houston. For our corporate guests, our accommodations come well-equipped with a number of great amenities like complimentary high-speed Internet access and a 24-hour Business Center with copy, fax, e-mail and print services....