Welcome to our recently constructed Holiday Inn Express® in Chesterfield, MO Hotel! Our Chesterfield, MO hotel is conveniently located on I-64 just off exit 17 and only 23 miles west of downtown St. Louis.nBusiness travelers will appreciate our hotel location near major companies such as St. Luke’s Hospital, Mercy Hospital, Barnes Jewish Hospital, Pfizer, Centene, Instituform, Aegion, Bayer, Reinsurance Group of America, Mark Andy and Amdocs. Staying at Holiday Inn Express & Suites St. Louis-Chesterfield will make it easier to visit popular area attractions like Six Flags St. Louis Amusement Park, Gateway Motorsports Park, Anheuser Busch Brewery, St. Louis Gateway...