Boasting a peaceful location in a quiet setting, the Hampton Inn Poplar Bluff hotel is only three miles from shops, restaurants and entertainment in the city center. Situated just off Highway 67, our welcoming Poplar Bluff hotel offers fantastic connectivity to St. Louis, Missouri and Little Rock, Arkansas. We are also within walking distance of Three Rivers College, and less than two miles from the new Poplar Bluff Regional Medical Center. Feel at home in a comfortable and modern guest room or suite, equipped with free WiFi, an ergonomic desk, a flat-screen TV, a radio alarm clock, and a bar...