Adventure awaits at Travelodge by Wyndham Santee, conveniently located off exit 98 on I-95. Our cozy hotel sits in central South Carolina, close to Lake Marion. Discover hiking trails and fishing at Santee State Park or head to the Santee National Wildlife Refuge for even more outdoor fun. Whether you are here for boating on the lake, a business trip, or just passing through, we welcome you with free high-speed WiFi, free continental breakfast and a seasonal outdoor pool.