Stay at our newly renovated Holiday Inn Express & Suites-Blythewood, South Carolina Blythewood is a suburb of Columbia, South Carolina’s capital city. Our historic city is a thriving metropolitan area. Columbia is a city with a proud tradition blending the old with the new, preserving the past while providing an exciting future.nHoliday Inn Express is located in the northeast side of Columbia, off I-77 Blythewood Road (Exit #27), just twenty minutes from downtown Columbia and Fort Jackson. Our close proximity to Providence Hospital, The University Club, Crickentree, CSC Corporation, Spirax-Sarco, Ben Arnold, Koyo, Winnsboro, SC and many more, makes our...